Is There a Temporal Relationship Between Outdoor Alternaria alternata Spore Counts and Specific IgE Alternaria alternata Levels?
نویسندگان
چکیده
منابع مشابه
Alternaria alternata transcription factor CmrA controls melanization and spore development.
Melanin is a black pigment widely distributed across the kingdoms, from bacterial to human. The filamentous fungus Alternaria alternata is a typical 'black fungus', which produces melanin in its hyphal and especially its asexual spore cell walls. Its biosynthesis follows the dihydroxynaphthalene (DHN) pathway with 1,8-DHN as an intermediate. Two genes, encoding a polyketide synthase (pksA) and ...
متن کاملA review of Alternaria alternata sensitivity.
Sensitivity to fungi is a major risk factor for the development of asthma. However, the prevalence of fungal sensitivity in asthma is not completely understood. Nonetheless upward of 80% of asthmatic patients may be sensitized to one or more fungi. Fungal exposure occurs primarily from outdoors sources, but can occur in the indoor environment as well. Assessment of fungal exposure requires a mu...
متن کاملSpecific IgE against Alternaria alternata in atopic dermatitis and asthma patients.
Alternaria alternata (A. alternata) is one of the most common airborne fungi in outdoor and indoor environment. A. alternata has also considered as an aeroallergen. So, it could be responsible for an allergen release and may be responsible for allergic reactions in sensitive patients. The aim of this study was the analyzing of specific IgE against A. alternata in atopic dermatitis (AD) and asth...
متن کاملEstablishment of CRISPR/Cas9 in Alternaria alternata.
The filamentous fungus Alternaria alternata is a potent producer of many secondary metabolites, some of which like alternariol or alternariol-methyl ether are toxic and/or cancerogenic. Many Alternaria species do not only cause post-harvest losses of food and feed, but are aggressive plant pathogens. Despite the great economic importance and the large number of research groups working with the ...
متن کاملCorrelation between Alt a 1 levels and clinical symptoms in Alternaria alternata-monosensitized patients.
BACKGROUND Alternaria alternata is a risk factor for developing asthma.Alt a 1, which has been described as the major allergen in A alternata, shows a good correlation with A alternata spores only when they have germinated. OBJECTIVES The objective of this study was to determine the correlation between spore counts and clinical symptoms in patients with allergic asthma and/or rhinitis monosen...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2016
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2015.12.099